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The Science Behind GLP-1 Medicines

An exploration of how GLP-1 medicines function and their effects on the body.

Mechanism of Action

GLP-1 medicines mimic the hormone GLP-1, which is released by the gut after eating. They help to lower blood sugar levels, reduce appetite, and prolong feelings of fullness. This mechanism makes them effective for managing both diabetes and weight.

Dual-Action Medicines

Some GLP-1 medicines are dual-action, meaning they also incorporate GIP, another hormone that enhances their effects. This combination can provide additional benefits for patients.

Research on GLP-1s and Heart Health

Emerging research suggests that GLP-1 medicines may have benefits beyond blood sugar control, including potential positive effects on heart and kidney health. However, this area is still being studied, and patients should consult their clinicians about their specific risks and benefits.

Frequently asked questions

GLP-1s act on appetite centres in the brain, reducing the constant mental chatter about food and helping to control hunger.
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