Metronidazole (topical)
Synonyms
Approved Treatment Indication:
Pseudomembranous Enterocolitis, Bacterial Endocarditis, Bacterial Meningitis, Abscess, Rosacea, Surgical Wound Infection, Trichomonas Vaginitis, Bacterial Vaginosis, Bacteroides Infections, Amebiasis, Sepsis, Giardiasis, Helicobacter Infections
Summary
What conditions metronidazole is used for
Metronidazole is used to treat infections caused by bacteria and parasites, which are tiny organisms that can cause disease. It's commonly prescribed for conditions like bacterial vaginosis, which is an infection of the vagina, trichomoniasis, which is a sexually transmitted infection, and certain gastrointestinal infections, which affect the stomach and intestines.
How metronidazole works in the body
Metronidazole works by entering the cells of bacteria and parasites and interfering with their DNA, which is the genetic material that controls cell functions. This action stops the growth and reproduction of these organisms, helping to eliminate the infection.
Directions for Use
The usual starting dose of metronidazole for adults is 500 mg taken twice daily. It's usually taken by mouth in tablet form, which means you swallow it whole. The frequency and duration depend on the condition being treated, and your doctor will provide specific instructions.
The most commonly observed adverse effects of metronidazole
Common side effects of metronidazole include nausea, which is feeling sick to your stomach, a metallic taste in the mouth, and diarrhea, which is loose or watery stools. These effects are usually mild and temporary.
Warnings and Precautions
Avoid alcohol while taking metronidazole, as it can cause unpleasant reactions like nausea and vomiting. Do not take metronidazole if you're allergic to it or its ingredients. Serious allergic reactions require immediate medical help. Always inform your doctor about any other medications you're taking to avoid potential interactions.
Drug Status
Government Approvals
WHO Essential Medicine
Known Teratogen
Pharmaceutical Class
