Metoclopramide (inhalant)
Synonyms
Approved Treatment Indication:
Gastroesophageal Reflux, Postoperative Nausea and Vomiting, Gastroparesis
Summary
What conditions metoclopramide is used for
Metoclopramide is used to treat nausea and vomiting, which are feelings of sickness and the act of throwing up, often related to chemotherapy or surgery. It also treats gastroparesis, which is a condition where the stomach empties slowly, causing bloating and discomfort.
How metoclopramide works in the body
Metoclopramide works by blocking dopamine receptors, which are parts of the brain that send signals causing nausea. This action helps reduce nausea and vomiting. It also increases stomach and intestinal movement, helping food move more quickly through the digestive system.
Directions for Use
The usual starting dose for adults is 10 mg, taken 30 minutes before meals and at bedtime, up to four times a day. It can be taken with or without food. Metoclopramide tablets should not be crushed, and it's important to follow your doctor's instructions.
The most commonly observed adverse effects of metoclopramide
Common side effects of metoclopramide include drowsiness, which is feeling sleepy, fatigue, which is feeling tired, and restlessness, which is feeling unable to relax. These effects are usually mild and temporary.
Warnings and Precautions
Metoclopramide can cause tardive dyskinesia, which involves involuntary muscle movements, especially with long-term use. It should not be used if you have a history of this condition or a bowel obstruction, which is a blockage in the intestines. Always inform your doctor about your medical history.
Drug Status
Government Approvals
WHO Essential Medicine
Known Teratogen
Pharmaceutical Class
