Buprenorphine (topical)
Synonyms
Approved Treatment Indication:
Pain, Heroin Dependence
Summary
What conditions buprenorphine is used for
Buprenorphine is used to treat opioid dependence, which is a condition where a person is addicted to opioids. It helps reduce cravings and withdrawal symptoms, making it easier for people to stop using opioids. It is often part of a comprehensive treatment plan that includes counseling and support.
How buprenorphine works in the body
Buprenorphine works by partially activating opioid receptors in the brain, which are parts of the brain that respond to opioids. This helps reduce cravings and withdrawal symptoms without producing the full effects of other opioids, making it effective for treating opioid dependence while reducing the risk of misuse.
Directions for Use
The usual starting dose of buprenorphine for adults is 2 to 8 mg per day, taken once daily. It is usually taken as a tablet or film placed under the tongue, which is a method called sublingual administration. Your doctor may adjust your dose based on your response and needs.
The most commonly observed adverse effects of buprenorphine
Common side effects of buprenorphine include nausea, which is feeling sick to your stomach, headache, and constipation, which is difficulty in passing stools. These effects can vary from person to person and are usually mild to moderate. If you notice new symptoms, talk with your doctor.
Warnings and Precautions
Buprenorphine can cause respiratory depression, which is slow or difficult breathing, especially if taken with other sedatives or alcohol. It can also be habit-forming, leading to dependence. It should not be used in people with severe respiratory depression or those allergic to the drug.
Drug Status
Government Approvals
WHO Essential Medicine
Known Teratogen
Pharmaceutical Class
